Chloe Rapp - Biochemistry
PhD Candidate
Country of Origin: Stouffville, Ontario Canada
Pre-MSc/PhD Education: Ryerson University Bachelor of Biology
Recent Research Experience:
In my undergrad I volunteered in Marie Killeen's genetics lab where I studied the nervous system development of C. elegans, specifically a putative transmembrane protein called ENU-3. ENU-3 is also an important protein in the process of apoptosis in the gonad of this organism. The theoretical domains of ENU-3 indicate that it is located in a membrane. My research involved determining which subcellular location ENU-3 is present in, as well as its interacting partners within the cell. In addition, I was also looking at the expression pattern of ENU-3 within the gonad to determine its role in apoptosis.
Current Research:
Currently researching the mechanism of mutations of a family of anion transport proteins, Solute Carrier Family 26 (SLC26), and how they lead to an array of human diseases. I have also identified a novel role for N-glycosylation (sugar modifications) on SLC26 proteins in conferring stability at the plasma membrane.
Why Faculty of Medicine?
I entered the Faculty of Medicine because I am passionate about addressing problems and questions in science related to human diseases and working towards developing realistic solutions. My current goal is to characterize mutation mechanisms that can help to develop therapeutics for many membrane protein diseases while completing my PhD.
Future Education Plans and/or Career Goals:
My future career goal after I graduate is to leave academia and become a Medical Sciences Liaison where my job would be to discuss new research and work towards bridging the gap between scientists and the lay community.